Double Heterozygosity of BRCA2 and STK11 in Familial Breast Cancer Detected by Exome Sequencing

BACKGROUND: Germ-line mutations of BRCA1 and BRCA2 genes are responsible for approximately 25–30% of dominantly inherited familial breast cancers; still a big part of genetic component is unknown. The aim of this study was to investigate genetic causes of familial breast cancer in a pedigree with re...

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Bibliografiske detaljer
Udgivet i:Iran J Public Health
Main Authors: ATAEI-KACHOUEI, Mojgan, NADAF, Javad, AKBARI, Mohammad Taghi, ATRI, Morteza, MAJEWSKI, Jacek, RIAZALHOSSEINI, Yasser, GARSHASBI, Masoud
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644579/
https://ncbi.nlm.nih.gov/pubmed/26576347
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