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Activation of glucocorticoid receptors in Müller glia is protective to retinal neurons and suppresses microglial reactivity

Reactive microglia and macrophages are prevalent in damaged retinas. Glucocorticoid signaling is known to suppress inflammation and the reactivity of microglia and macrophages. In the vertebrate retina, the glucocorticoid receptor (GCR) is known to be activated and localized to the nuclei of Müller...

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Publicat a:Exp Neurol
Autors principals: Gallina, Donika, Zelinka, Christopher Paul, Cebulla, Colleen, Fischer, Andy J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644458/
https://ncbi.nlm.nih.gov/pubmed/26272753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.08.007
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