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Activation of glucocorticoid receptors in Müller glia is protective to retinal neurons and suppresses microglial reactivity

Reactive microglia and macrophages are prevalent in damaged retinas. Glucocorticoid signaling is known to suppress inflammation and the reactivity of microglia and macrophages. In the vertebrate retina, the glucocorticoid receptor (GCR) is known to be activated and localized to the nuclei of Müller...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Gallina, Donika, Zelinka, Christopher Paul, Cebulla, Colleen, Fischer, Andy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644458/
https://ncbi.nlm.nih.gov/pubmed/26272753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.08.007
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