The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

The Hippo signaling pathway controls organ size and tumorigenesis through a kinase cascade that inactivates Yes-associated protein (YAP). Here, we show that YAP plays a central role in controlling the progression of cervical cancer. Our results suggest that YAP expression is associated with a poor p...

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Veröffentlicht in:EMBO Mol Med
Hauptverfasser: He, Chunbo, Mao, Dagan, Hua, Guohua, Lv, Xiangmin, Chen, Xingcheng, Angeletti, Peter C, Dong, Jixin, Remmenga, Steven W, Rodabaugh, Kerry J, Zhou, Jin, Lambert, Paul F, Yang, Peixin, Davis, John S, Wang, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644376/
https://ncbi.nlm.nih.gov/pubmed/26417066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404976
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