RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

Tumor-educated blood platelets (TEPs) are implicated as central players in the systemic and local responses to tumor growth, thereby altering their RNA profile. We determined the diagnostic potential of TEPs by mRNA sequencing of 283 platelet samples. We distinguished 228 patients with localized and...

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Publicado no:Cancer Cell
Main Authors: Best, Myron G., Sol, Nik, Kooi, Irsan, Tannous, Jihane, Westerman, Bart A., Rustenburg, François, Schellen, Pepijn, Verschueren, Heleen, Post, Edward, Koster, Jan, Ylstra, Bauke, Ameziane, Najim, Dorsman, Josephine, Smit, Egbert F., Verheul, Henk M., Noske, David P., Reijneveld, Jaap C., Nilsson, R. Jonas A., Tannous, Bakhos A., Wesseling, Pieter, Wurdinger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644263/
https://ncbi.nlm.nih.gov/pubmed/26525104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.09.018
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