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Mathematical analysis of the sodium sensitivity of the human histamine H(3) receptor
PURPOSE: It was shown by several experimental studies that some G protein coupled receptors (GPCR) are sensitive to sodium ions. Furthermore, mutagenesis studies or the determination of crystal structures of the adenosine A(2A) or δ-opioid receptor revealed an allosteric Na(+) binding pocket near to...
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| Publicat a: | In Silico Pharmacol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4644138/ https://ncbi.nlm.nih.gov/pubmed/27502620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40203-014-0001-y |
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