Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA

Helicobacter pylori is a leading cause of peptic ulceration and gastric cancer worldwide. To achieve colonization of the stomach, this Gram-negative bacterium adheres to Lewis(b) (Le(b)) antigens in the gastric mucosa using its outer membrane protein BabA. Structural information for BabA has been el...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Hage, Naim, Howard, Tina, Phillips, Chris, Brassington, Claire, Overman, Ross, Debreczeni, Judit, Gellert, Paul, Stolnik, Snow, Winkler, G. Sebastiaan, Falcone, Franco H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643811/
https://ncbi.nlm.nih.gov/pubmed/26601230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500315
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