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Dynamics of Lewis b Binding and Sequence Variation of the babA Adhesin Gene during Chronic Helicobacter pylori Infection in Humans

Helicobacter pylori undergoes rapid microevolution during chronic infection, but very little is known about how this affects host interaction factors. The best-studied adhesin of H. pylori is BabA, which mediates binding to the blood group antigen Lewis b [Le(b)]. To study the dynamics of Le(b) adhe...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Nell, Sandra, Kennemann, Lynn, Schwarz, Sandra, Josenhans, Christine, Suerbaum, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271554/
https://ncbi.nlm.nih.gov/pubmed/25516619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02281-14
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