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Extension of the generic amyloid hypothesis to nonproteinaceous metabolite assemblies

The accumulation of amyloid fibrils is the hallmark of several major human diseases. Although the formation of these supramolecular entities has previously been associated with proteins and peptides, it was later demonstrated that even phenylalanine, a single amino acid, can form fibrils that have a...

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書目詳細資料
發表在:Sci Adv
Main Authors: Shaham-Niv, Shira, Adler-Abramovich, Lihi, Schnaider, Lee, Gazit, Ehud
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643800/
https://ncbi.nlm.nih.gov/pubmed/26601224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500137
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