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atSNP: transcription factor binding affinity testing for regulatory SNP detection

Motivation: Genome-wide association studies revealed that most disease-associated single nucleotide polymorphisms (SNPs) are located in regulatory regions within introns or in regions between genes. Regulatory SNPs (rSNPs) are such SNPs that affect gene regulation by changing transcription factor (T...

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Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Zuo, Chandler, Shin, Sunyoung, Keleş, Sündüz
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643619/
https://ncbi.nlm.nih.gov/pubmed/26092860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv328
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