Thymidine kinase mutants obtained by random sequence selection.
Knowledge of the catalytic properties and structural information regarding the amino acid residues that comprise the active site of an enzyme allows one, in principle, to use site-specific mutagenesis to construct genes that encode enzymes with altered functions. However, such information about most...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1993
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8387207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4012 |
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