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p38α MAPK is required for arsenic-induced cell transformation

Arsenic exposure has been reported to cause neoplastic transformation through the activation of PcG proteins. In the present study, we show that activation of p38α mitogen-activated protein kinase (MAPK) is required for arsenic-induced neoplastic transformation. Exposure of cells to 0.5 µM arsenic i...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Kim, Hong-Gyum, Shi, Chengcheng, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643444/
https://ncbi.nlm.nih.gov/pubmed/25969347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22331
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