Polycomb (PcG) Proteins, BMI1 and SUZ12, Regulate Arsenic-induced Cell Transformation

Inorganic arsenic is a well-documented human carcinogen associated with cancers of the skin, lung, liver, and bladder. However, the underlying mechanisms explaining the tumorigenic role of arsenic are not well understood. The present study explored a potential mechanism of cell transformation induce...

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Bibliographic Details
Main Authors: Kim, Hong-Gyum, Kim, Dong Joon, Li, Shengqing, Lee, Kun Yeong, Li, Xiang, Bode, Ann M., Dong, Zigang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442524/
https://ncbi.nlm.nih.gov/pubmed/22843710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360362
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