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Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions
The physical properties of two-dimensional (2D) extracellular matrices (ECMs) modulate cell adhesion dynamics and motility, but little is known about the roles of local microenvironmental differences in three-dimensional (3D) ECMs. Here we generate 3D collagen gels of varying matrix microarchitectur...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643399/ https://ncbi.nlm.nih.gov/pubmed/26548801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9720 |
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