Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions

Polarization of cells into a protrusive front and a retracting cell body is the hallmark of mesenchymal-like cell migration. Many mRNAs are localized to protrusions, but it is unclear to what degree mRNA localization contributes toward protrusion formation. We performed global quantitative analysis...

詳細記述

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書誌詳細
出版年:Dev Cell
主要な著者: Mardakheh, Faraz K., Paul, Angela, Kümper, Sandra, Sadok, Amine, Paterson, Hugh, Mccarthy, Afshan, Yuan, Yinyin, Marshall, Christopher J.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643311/
https://ncbi.nlm.nih.gov/pubmed/26555054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.10.005
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