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Copper-mediated N-Arylation of Methyl 2-Aminothiophene-3-carboxylate with Organoboron Reagents

A practical protocol for the synthesis of N-arylated methyl 2-aminothiophene-3-carboxylate has been developed via Chan-Lam cross-coupling. The desired products were synthesized by cross-coupling of methyl 2-aminothiophene-3-carboxylate with both arylboronic acids and potassium aryltrifluoroborate sa...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Rizwan, Komal, Karakaya, Idris, Heitz, Drew, Zubair, Muhammad, Rasool, Nasir, Molander, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643285/
https://ncbi.nlm.nih.gov/pubmed/26576065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.10.080
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