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Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening
Alzheimer’s disease (AD) therapeutics based on the amyloid hypothesis have shown minimal efficacy in patients, suggesting that the activity of amyloid beta (Aβ) represents only one aspect of AD pathogenesis. Since neuroinflammation is thought to play an important role in AD, we hypothesized that cyt...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643219/ https://ncbi.nlm.nih.gov/pubmed/26564777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16622 |
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