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Evolution and Emergence of Enteroviruses through Intra- and Inter-species Recombination: Plasticity and Phenotypic Impact of Modular Genetic Exchanges in the 5’ Untranslated Region

Genetic recombination shapes the diversity of RNA viruses, including enteroviruses (EVs), which frequently have mosaic genomes. Pathogenic circulating vaccine-derived poliovirus (cVDPV) genomes consist of mutated vaccine poliovirus (PV) sequences encoding capsid proteins, and sequences encoding nons...

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Publicat a:PLoS Pathog
Autors principals: Muslin, Claire, Joffret, Marie-Line, Pelletier, Isabelle, Blondel, Bruno, Delpeyroux, Francis
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643034/
https://ncbi.nlm.nih.gov/pubmed/26562151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005266
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