CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock

Intracellular circadian clocks, composed of clock genes that act in transcription-translation feedback loops, drive global rhythmic expression of the mammalian transcriptome and allow an organism to anticipate to the momentum of the day. Using a novel clock-perturbing peptide, we established a pivot...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Tamaru, Teruya, Hattori, Mitsuru, Honda, Kousuke, Nakahata, Yasukazu, Sassone-Corsi, Paolo, van der Horst, Gijsbertus T. J., Ozawa, Takeaki, Takamatsu, Ken
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642984/
https://ncbi.nlm.nih.gov/pubmed/26562092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002293
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