The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus

Synaptic target specificity, whereby neurons make distinct types of synapses with different target cells, is critical for brain function, yet the mechanisms driving it are poorly understood. In this study, we demonstrate Kirrel3 regulates target-specific synapse formation at hippocampal mossy fiber...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Martin, E Anne, Muralidhar, Shruti, Wang, Zhirong, Cervantes, Diégo Cordero, Basu, Raunak, Taylor, Matthew R, Hunter, Jennifer, Cutforth, Tyler, Wilke, Scott A, Ghosh, Anirvan, Williams, Megan E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642954/
https://ncbi.nlm.nih.gov/pubmed/26575286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09395
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