Specific Disruption of Hippocampal Mossy Fiber Synapses in a Mouse Model of Familial Alzheimer's Disease

The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear if specific hippocampal synapses are parti...

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Detalhes bibliográficos
Main Authors: Wilke, Scott A., Raam, Tara, Antonios, Joseph K., Bushong, Eric A., Koo, Edward H., Ellisman, Mark H., Ghosh, Anirvan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890281/
https://ncbi.nlm.nih.gov/pubmed/24454724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084349
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