Specific Disruption of Hippocampal Mossy Fiber Synapses in a Mouse Model of Familial Alzheimer's Disease

The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear if specific hippocampal synapses are parti...

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Bibliografiske detaljer
Main Authors: Wilke, Scott A., Raam, Tara, Antonios, Joseph K., Bushong, Eric A., Koo, Edward H., Ellisman, Mark H., Ghosh, Anirvan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890281/
https://ncbi.nlm.nih.gov/pubmed/24454724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084349
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