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Sex-specific Mediation of Opioid-induced Hyperalgesia by the Melanocortin-1 Receptor

BACKGROUND: N-Methyl-d-aspartate receptor antagonists reverse hyperalgesia during morphine infusion in male mice only. Because the melanocortin-1 receptor can act as a female-specific counterpart to N-methyl-d-aspartate receptors in κ-opioid analgesic mechanisms, the authors assessed the contributio...

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Publicado en:Anesthesiology
Main Authors: Juni, Aaron, Cai, Minying, Stankova, Magda, Waxman, Amanda R., Arout, Caroline, Klein, Gad, Dahan, Albert, Hruby, Victor J., Mogil, Jeffrey S., Kest, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642894/
https://ncbi.nlm.nih.gov/pubmed/19996949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181c53849
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