Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules

Peptide splicing, in which two distant parts of a protein are excised and then ligated to form a novel peptide, can generate unique MHC class I–restricted responses. Because these peptides are not genetically encoded and the rules behind proteasomal splicing are unknown, it is difficult to predict t...

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Pubblicato in:J Immunol
Autori principali: Berkers, Celia R., de Jong, Annemieke, Schuurman, Karianne G., Linnemann, Carsten, Meiring, Hugo D., Janssen, Lennert, Neefjes, Jacques J., Schumacher, Ton N. M., Rodenko, Boris, Ovaa, Huib
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2015
Soggetti:
Antigen Recognition and Responses
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642839/
https://ncbi.nlm.nih.gov/pubmed/26401003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402455
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