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Activation of SphK1 by K6PC-5 Inhibits Oxygen–Glucose Deprivation/Reoxygenation-Induced Myocardial Cell Death

In the current study, we evaluated the potential effect of a novel sphingosine kinase 1 (SphK1) activator, K6PC-5, on oxygen–glucose deprivation (OGD)/reoxygenation-induced damages to myocardial cells. We demonstrated that K6PC-5 increased intracellular sphingosine-1-phosphate (S1P) content and rema...

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Detalhes bibliográficos
Publicado no:DNA Cell Biol
Main Authors: Shao, Jun-jie, Peng, Yi, Wang, Li-ming, Wang, Jian-kai, Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642826/
https://ncbi.nlm.nih.gov/pubmed/26308910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2015.2959
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