Preferential enhancement of older human T cell cytokine generation, Chemotaxis, proliferation and survival by lenalidomide

Lenalidomide, an analog of thalidomide, modified responses of stimulated T cells from healthy young (ages 21–40 years) and old (≥age 65 years) subjects. At 0.03 μM to 1 μM, lenalidomide enhanced generation of IL-2 and IFN-γ by T cell receptor-stimulated T cells of young subjects up to respective max...

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Publicado no:Clin Immunol
Main Authors: Huang, Mei-Chuan, Greig, Nigel H., Luo, Weiming, Tweedie, David, Schwartz, Janice B., Longo, Dan L., Ferrucci, Luigi, Ershler, William B., Goetzl, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642720/
https://ncbi.nlm.nih.gov/pubmed/21130040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.11.002
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