Myeloid-related protein 8 induces self-tolerance and cross-tolerance to bacterial infection via TLR4- and TLR2-mediated signal pathways

Myeloid-related protein 8 (Mrp8) is the active component of Mrp8/14 protein complex released by phagocytes at the site of infection and stimulates inflammatory responses. However, it is unclear whether Mrp8 could induce self-tolerance and cross-tolerance to bacterial infection. Here we report that M...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Coveney, Andrew P., Wang, Wei, Kelly, Justin, Hua Liu, Jing, Blankson, Siobhan, Di Wu, Qiong, Paul Redmond, H., Huai Wang, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642578/
https://ncbi.nlm.nih.gov/pubmed/26329314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13694
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