Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

A central tenet of signal transduction in eukaryotic cells is that extra-cellular ligands activate specific cell surface receptors, which orchestrate downstream responses. This ‘’protein-centric” view is increasingly challenged by evidence for the involvement of specialized membrane domains in signa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nadeem, Aftab, Sanborn, Jeremy, Gettel, Douglas L., James, Ho C. S., Rydström, Anna, Ngassam, Viviane N., Klausen, Thomas Kjær, Pedersen, Stine Falsig, Lam, Matti, Parikh, Atul N., Svanborg, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642337/
https://ncbi.nlm.nih.gov/pubmed/26561036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16432
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