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Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care

Randomized clinical trials (RCTs) are conducted to guide clinicians’ selection of therapies for individual patients. Currently, RCTs in critical care often report an overall mean effect and selected individual subgroups. Yet work in other fields suggests that such reporting practices can be improved...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Iwashyna, Theodore J., Burke, James F., Sussman, Jeremy B., Prescott, Hallie C., Hayward, Rodney A., Angus, Derek C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642199/
https://ncbi.nlm.nih.gov/pubmed/26177009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201411-2125CP
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