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Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care

Randomized clinical trials (RCTs) are conducted to guide clinicians’ selection of therapies for individual patients. Currently, RCTs in critical care often report an overall mean effect and selected individual subgroups. Yet work in other fields suggests that such reporting practices can be improved...

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Pubblicato in:Am J Respir Crit Care Med
Autori principali: Iwashyna, Theodore J., Burke, James F., Sussman, Jeremy B., Prescott, Hallie C., Hayward, Rodney A., Angus, Derek C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642199/
https://ncbi.nlm.nih.gov/pubmed/26177009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201411-2125CP
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