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Mammalian target of rapamycin complex 1 (mTORC1) is required for mouse spermatogonial differentiation in vivo
Spermatogonial stem cells (SSCs) must balance self-renewal with production of transit-amplifying progenitors that differentiate in response to retinoic acid (RA) before entering meiosis. This self-renewal vs. differentiation spermatogonial fate decision is critical for maintaining tissue homeostasis...
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| Udgivet i: | Dev Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641790/ https://ncbi.nlm.nih.gov/pubmed/26254600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.08.004 |
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