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Interstitial Fluid Flow Increases Hepatocellular Carcinoma Cell Invasion through CXCR4/CXCL12 and MEK/ERK Signaling

Hepatocellular carcinoma (HCC) is the most common form of liver cancer (~80%), and it is one of the few cancer types with rising incidence in the United States. This highly invasive cancer is very difficult to detect until its later stages, resulting in limited treatment options and low survival rat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shah, Arpit D., Bouchard, Michael J., Shieh, Adrian C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641731/
https://ncbi.nlm.nih.gov/pubmed/26560447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142337
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