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Toll-Like Receptor 2 Targeted Rectification of Impaired CD8(+) T Cell Functions in Experimental Leishmania donovani Infection Reinstates Host Protection
Leishmania donovani, a protozoan parasite, causes the disease visceral leishmanisis (VL), characterized by inappropriate CD8(+) T-cell activation. Therefore, we examined whether the Toll-like Receptor 2 (TLR2) ligand Ara-LAM, a cell wall glycolipid from non-pathogenic Mycobacterium smegmatis, would...
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| Gepubliceerd in: | PLoS One |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641719/ https://ncbi.nlm.nih.gov/pubmed/26559815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142800 |
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