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Eye Movement Deficits Are Consistent with a Staging Model of pTDP-43 Pathology in Amyotrophic Lateral Sclerosis

BACKGROUND: The neuropathological process underlying amyotrophic lateral sclerosis (ALS) can be traced as a four-stage progression scheme of sequential corticofugal axonal spread. The examination of eye movement control gains deep insights into brain network pathology and provides the opportunity to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gorges, Martin, Müller, Hans-Peter, Lulé, Dorothée, Del Tredici, Kelly, Brettschneider, Johannes, Keller, Jürgen, Pfandl, Katharina, Ludolph, Albert C., Kassubek, Jan, Pinkhardt, Elmar H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641606/
https://ncbi.nlm.nih.gov/pubmed/26559944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142546
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