A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates

By replacing the central thiophene unit of an anionic pentameric oligothiophene with other heterocyclic moities, a palette of pentameric thiophene-based ligands with distinct fluorescent properties were synthesized. All ligands displayed superior selectivity towards recombinant amyloid fibrils as we...

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Detalles Bibliográficos
Publicado en:Chemistry
Autores principales: Shirani, Hamid, Linares, Mathieu, Sigurdson, Christina J, Lindgren, Mikael, Norman, Patrick, Nilsson, K Peter R
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641461/
https://ncbi.nlm.nih.gov/pubmed/26388448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201502999
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