Retinoic acid is a negative regulator of the Epstein-Barr virus protein (BZLF1) that mediates disruption of latent infection.

Disruption of latent Epstein-Barr virus (EBV) infection is induced by the key immediate-early protein BZLF1 (or Z, a member of the basic leucine-zipper family), which transactivates the viral early promoters. Viral reactivation is marked by renewed synthesis of early gene products such as EBV early...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sista, N D, Pagano, J S, Liao, W, Kenney, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8387200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.3894
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