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Retinoic acid is a negative regulator of the Epstein-Barr virus protein (BZLF1) that mediates disruption of latent infection.

Disruption of latent Epstein-Barr virus (EBV) infection is induced by the key immediate-early protein BZLF1 (or Z, a member of the basic leucine-zipper family), which transactivates the viral early promoters. Viral reactivation is marked by renewed synthesis of early gene products such as EBV early...

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Main Authors: Sista, N D, Pagano, J S, Liao, W, Kenney, S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC46412/
https://ncbi.nlm.nih.gov/pubmed/8387200
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