The relation of circulating CC16 to lung function growth, decline, and development of COPD across the lifespan

BACKGROUND: Low serum levels of the anti-inflammatory club cell secretory protein (CC16) have been associated with an accelerated FEV1 decline in COPD. Whether low circulating CC16 precedes lung function deficits and incidence of COPD in the general population is unknown. METHODS: We used longitudin...

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Publicado no:Lancet Respir Med
Main Authors: Guerra, Stefano, Halonen, Marilyn, Vasquez, Monica M, Spangenberg, Amber, Stern, Debra A., Morgan, Wayne J., Wright, Anne L., Lavi, Iris, Tarès, Lluïsa, Carsin, Anne-Elie, Dobaño, Carlota, Barreiro, Esther, Zock, Jan-Paul, Martínez-Moratalla, Jesús, Urrutia, Isabel, Sunyer, Jordi, Keidel, Dirk, Imboden, Medea, Probst-Hensch, Nicole, Hallberg, Jenny, Melén, Erik, Wickman, Magnus, Bousquet, Jean, Belgrave, Danielle C. M., Simpson, Angela, Custovic, Adnan, Antó, Josep M, Martinez, Fernando D
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640928/
https://ncbi.nlm.nih.gov/pubmed/26159408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(15)00196-4
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