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Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos

Oocyte maturation and embryonic development are sensitive to DNA damage. Compared with somatic cells or oocytes, little is known about the response to DNA damage in early preimplantation embryos. In this study, we examined DNA damage checkpoints and DNA repair mechanisms in parthenogenetic preimplan...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, HaiYang, Luo, YiBo, Lin, ZiLi, Lee, In-Won, Kwon, Jeongwoo, Cui, Xiang-Shun, Kim, Nam-Hyung
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640854/
https://ncbi.nlm.nih.gov/pubmed/26556501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142561
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