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CRISPR/Cas9 as Tool for Functional Study of Genes Involved in Preimplantation Embryo Development

The CRISPR/Cas9 system has proven to be an efficient gene-editing tool for genome modification of cells and organisms. However, the applicability and efficiency of this system in pig embryos have not been studied in depth. Here, we aimed to remove porcine OCT4 function as a model case using the CRIS...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kwon, Jeongwoo, Namgoong, Suk, Kim, Nam-Hyung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361403/
https://ncbi.nlm.nih.gov/pubmed/25775469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120501
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