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Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression

Pancreatic Ductal Adenocarcinoma (PDAC) is a highly lethal malignancy due to its propensity to invade and rapidly metastasize and remains very difficult to manage clinically. One major hindrance towards a better understanding of PDAC is the lack of molecular data sets and models representative of en...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xie, Tao, Musteanu, Monica, Lopez-Casas, Pedro P., Shields, David J., Olson, Peter, Rejto, Paul A., Hidalgo, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640827/
https://ncbi.nlm.nih.gov/pubmed/26555578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142631
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