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VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish

Physiological functions of vascular endothelial growth factor (VEGF)-B remain an enigma, and deletion of the Vegfb gene in mice lacks an overt phenotype. Here we show that knockdown of Vegfba, but not Vegfbb, in zebrafish embryos by specific morpholinos produced a lethal phenotype owing to vascular...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Jensen, Lasse D., Nakamura, Masaki, Bräutigam, Lars, Li, Xuri, Liu, Yizhi, Samani, Nilesh J., Cao, Yihai
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640767/
https://ncbi.nlm.nih.gov/pubmed/26483474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510245112
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