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Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
To save time and cost for drug discovery, a paradigm shift in cardiotoxicity testing is required. We introduce a novel screening system for drug-induced arrhythmogenic risk that combines in vitro pharmacological assays and a multiscale heart simulator. For 12 drugs reported to have varying cardiotox...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640654/ https://ncbi.nlm.nih.gov/pubmed/26601174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1400142 |
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