FGFR1 Amplification Is Often Homogeneous and Strongly Linked to the Squamous Cell Carcinoma Subtype in Esophageal Carcinoma

BACKGROUND AND AIMS: Amplification of the fibroblast growth factor receptor 1 (FGFR1) is believed to predict response to multi-kinase inhibitors targeting FGFR1. Esophageal cancer is an aggressive disease, for which novel targeted therapies are highly warranted. METHODS: This study was designed to i...

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Опубликовано в: :PLoS One
Главные авторы: von Loga, Katharina, Kohlhaussen, Jule, Burkhardt, Lia, Simon, Ronald, Steurer, Stefan, Burdak-Rothkamm, Susanne, Jacobsen, Frank, Sauter, Guido, Krech, Till
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640518/
https://ncbi.nlm.nih.gov/pubmed/26555375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141867
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