Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates.

The antiviral activity of antisense oligodeoxynucleotide phosphorothioates complementary to the tat gene, the gag mRNA, and the rev mRNA were studied in a long-term infection model. Three antisense oligonucleotides directed to the splice-acceptor site of the tat gene failed to suppress human immunod...

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Main Authors: Lisziewicz, J, Sun, D, Metelev, V, Zamecnik, P, Gallo, R C, Agrawal, S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC46405/
https://ncbi.nlm.nih.gov/pubmed/8483903
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