Vascular permeability in cerebral cavernous malformations

Patients with the familial form of cerebral cavernous malformations (CCMs) are haploinsufficient for the CCM1, CCM2, or CCM3 gene. Loss of corresponding CCM proteins increases RhoA kinase-mediated endothelial permeability in vitro, and in mouse brains in vivo. A prospective case-controlled observati...

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Dades bibliogràfiques
Publicat a:J Cereb Blood Flow Metab
Autors principals: Mikati, Abdul G, Khanna, Omaditya, Zhang, Lingjiao, Girard, Romuald, Shenkar, Robert, Guo, Xiaodong, Shah, Akash, Larsson, Henrik BW, Tan, Huan, Li, Luying, Wishnoff, Matthew S, Shi, Changbin, Christoforidis, Gregory A, Awad, Issam A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640319/
https://ncbi.nlm.nih.gov/pubmed/25966944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.98
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