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Arginase I release from activated neutrophils induces peripheral immunosuppression in a murine model of stroke

Transient suppression of peripheral immunity is a major source of complication for patients suffering from ischemic stroke. The release of Arginase I (ArgI) from activated neutrophils has recently been associated with T-cell dysfunction in a number of pathologies. However, this pathway has not been...

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Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Sippel, Trisha R, Shimizu, Takeru, Strnad, Frank, Traystman, Richard J, Herson, Paco S, Waziri, Allen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640306/
https://ncbi.nlm.nih.gov/pubmed/25966956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.103
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