Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein

Owing to the frequent incidence of blast-induced traumatic brain injury (bTBI) in recent military conflicts, there is an urgent need to develop effective therapies for bTBI-related pathologies. Blood-brain barrier (BBB) breakdown has been reported to occur after primary blast exposure, making restor...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Hue, Christopher D, Cho, Frances S, Cao, Siqi, ”Dale” Bass, Cameron R, Meaney, David F, Morrison III, Barclay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640274/
https://ncbi.nlm.nih.gov/pubmed/25757751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.38
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