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Mechanism of glucocorticoid regulation of the intestinal tight junction barrier

A defective intestinal epithelial tight junction (TJ) barrier has been proposed as an important pathogenic factor contributing to the intestinal inflammation of Crohn's disease. Glucocorticoids are first-line therapeutic agents for the treatment of moderate to severe Crohn's disease. Gluco...

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Detalhes bibliográficos
Main Authors: Boivin, Michel A., Ye, Dongmei, Kennedy, John C., Al-Sadi, Rana, Shepela, Chris, Ma, Thomas Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724219/
https://ncbi.nlm.nih.gov/pubmed/17068119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00252.2006
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