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High T(3), Low T(4) Serum Levels in Mct8 Deficiency Are Not Caused by Increased Hepatic Conversion through Type I Deiodinase

BACKGROUND: The Allan-Herndon-Dudley syndrome is a severe psychomotor retardation accompanied by specific changes in circulating thyroid hormone levels (high T(3), low T(4)). These are caused by mutations in the thyroid hormone transmembrane transport protein monocarboxylate transporter 8 (MCT8). Ob...

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Detalles Bibliográficos
Publicado en:Eur Thyroid J
Autores principales: Wirth, Eva K., Rijntjes, Eddy, Meyer, Franziska, Köhrle, Josef, Schweizer, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640264/
https://ncbi.nlm.nih.gov/pubmed/26601078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381021
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