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The Protein Translocation Defect of MCT8(L291R) Is Rescued by Sodium Phenylbutyrate

INTRODUCTION: The monocarboxylate transporter 8 (MCT8; SLC16A2) is a specific transporter for thyroid hormones. MCT8 deficiency, formerly known as the Allan-Herndon-Dudley syndrome, is a rare genetic disease that leads to neurological impairments and muscle weakness. Current experimental treatment o...

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Bibliografiska uppgifter
I publikationen:Eur Thyroid J
Huvudupphovsmän: Braun, Doreen, Schweizer, Ulrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: S. Karger AG 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548921/
https://ncbi.nlm.nih.gov/pubmed/33088796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000507439
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